I am new to M.S. (diagnosed March 07) and still learning more each day. This question seems VERY elementary and I apologize. I have messages into my Neuro, the MSSociety and have read dozens of books, which seem to delve much deeper than something as basic as this. I was diagnosed after an MRI following a drastic exarcebation that took me to the emergency room. After all that drama, and after being on Avonex since April, I am curious about something: this week I have been feeling a numb (lft side) and a bit fatigued. And of course these things are standard for MSers. But do the existence of these "symptoms" indicate new "exacerbations?" I ask this because, as an Avonex user, I am VERY, VERY enthusiastic about all the good press and results this med gets and I am watching VERY closely to make sure I do not progress – MANY others have similar success with Avonex. And I plan to be one. But…DO these symptoms mean the drug IS NOT WORKING?? This is my MAIN fear/concern right now. Anyone?